The correlation between QT dispersion and ventricular arrhythmias in regular hemodialysis patients with renal failure

Abstract

Objectives To investigate the change of QT dispersion (QTd) in 65 patients with renal failure undergoing regular hemodialysis, the relationship between QTd and ventricular arrhythmia in those patients. Methods 65 hemodialysis patients were divided into two groups: patients with ventricular arrhythmia group and patients without ventricular arrhythmia group. ECG were carried out before and after dialysis, and QTd were calculated. Meanwhile, clinical parameters and indexes of laboratory examinations were recorded. Finally, experimental data were statistically analyzed. Results Before hemodialysis, QTd in patients with ventricular arrhythmias had a significant higher than in patients without ventricular arrhythmia(P<0.01). Post-hemodialysis values of QTd had a significant higher than pre-hemodialysis values(P<0.01). It is shown that the extension of QTd was correlated with the change of K+ concentration and CO2CP. Conclusions Increasing of QTd in hemodialysis patients may be related to the occurrence of ventricular arrhythmias. QTd extension during hemodialysis may due to the rapid change of K+ concentration and rapid correction of acidosis. Key words: Kidney Failure, Chronic; Renal Dialysis; Arrhythmias, Cardiac