Effect of metoprolol combined with benazepril on QT dispersion of patients with congestive heart failure and ventricular arrhythmia

Abstract

Objective To investigate the effect of metoprolol combined with benazepril on QT dispersion of patients with congestive heart failure and ventricular arrhythmia. Methods From July 2013 to July 2015, 98 patients with congestive heart failure and ventricular arrhythmia were randomly divided into two groups, with 49 cases in each group. The patients in the two groups were given routine treatment, and the control group was given benazepril treatment on basis of routine treatment, observation group was treated with benazepril combined with metoprolol. The clinical efficacy and cardiac function indexes were compared between the two groups. Results The total effective rate of the observation group was significantly higher than that of the control group, the difference was significant (P<0.05); the QT dispersion in the observation group was significantly lower than that in the control group, QT interval was significantly higher than that in the control group, the difference was significant (P<0.05). Conclusions Combined metoprolol and benazepril is help to enhance the clinical efficacy, reduce QT dispersion and contribute to the improvement of cardiac function, and it is worthy to be popularized. Key words: Metoprolol; Benazepril; Congestive heart failure; Ventricular arrhythmia; QT dispersion