Abstract
The work of Ramon on the flocculation of mixtures of diphtheria toxin and antitoxin has given us a new measure of toxin—the L f ; this is defined as the amount of toxin which with a unit of antitoxin flocculates in minimum time. Practically all the toxin and antitoxin in such an indicating mixture are carried down in the precipitate, and we may therefore consider that one L f of toxin combines with one unit of antitoxin to form a balanced compound of minimum solubility. From mixtures containing excess of toxin or antitoxin precipitates are formed containing an excess of one of these constitutents, the precipitation is delayed, and when the ratio is altered too far, altogether prevented.
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Schedule a callMore From: Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character
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