Abstract

Objective To explore the combined effects of lead and noise exposure on serum SOD and MDA levels.Methods Workers in group A (lead and noise exposure) and group B (noise exposure) had matched age,length of working and intensity of noise.The serum SOD and MDA levels were detected and compared between two groups.Results The serum SOD levels of group A and group B were (65.2 ± 16.3)U/ml,(63.8 ± 13.9)U/ml respectively,without significant difference between two groups (P > 0.05).The serum MDA levels of group A and group B were (6.81 ± 3.12) nmol/ml,(5.02 ± 2.36) nmol/ml respectively,with significant difference between two groups (P < 0.05).Conclusion Lead combined with noise exposure may worsen free radical impairment and lipid peroxidation. Key words: Lead; Noise; Combined effects; SOD; MDA

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