The clinical value of Tei index in the evaluation of left ventricular function of diabetic patients with normal LVEF

Abstract

Objective To observe the value of myocardial performance index (Tei index) in evaluating the left ventricular function in diabetic patients with normal left ventricular ejection fraction (LVEF),and to investigate its correlation with plasma N-terminal pro-brain natriuretic peptide (NT-proBNP).Methods 96 diabetic patients with normal LVEF were selected as the observation group,50 healthy persons were selected as control group.Left ventricular Tei index was measured by color Doppler ultrasound.The plasma NT-proBNP was detected.Results The Tei index,plasma level of NT-proBNP of the observation group were (0.49 ± 0.11),(397.6 ± 39.4) ng/L,those of the control group were (0.32 ± 0.07),(101.2 ± 18.4) ng/L,the differences between the two groups were statistically significant(t =11.357,1.992,all P ＜ 0.05).There was significant positive correlation between Tei index and plasma NT-proBNP in the observation group(r =0.661,P ＜ 0.05).Conclusion Combined determination of Tei index and plasma NT-proBNP can detect early myocardial damage in patients with diabetes mellitus. Key words: Diabetes; Tei index; NT-proBNP