The clinical value of endovascular stent in treatment of hepatic vein-type Budd-Chiari syndrome: a Meta analysis

Abstract

Objective To analyze the clinical significance of endovascular stents in treatment of hepatic vein type Budd-Chiari syndrome. Methods Newcastle-Ottawa Scale assessment method was used by carrying out the computer-based retrieval and collecting the documents about the endovascular stents in treatment of hepatic vein type Budd-Chiari syndrome at home and abroad, the searching time limit was set from January 1992 to July 2014, all of collected data were analyzed and summarized, and the Meta analysis was conducted for the diameter stenosis and blocking rate of postoperative endovascular stents and percutaneous transluminal angioplasty. Results After systematic retrieval based on search strategies, according to inclusion criteria, there were 6 Chinese papers and one English paper included, with a total of 534 patients. The Meta analysis was conducted for the diameter stenosis and blocking rate of postoperative endovascular stents and percutaneous transluminal angioplasty in those included papers. The results showed that, after combining the diameter stenosis and blocking rate of postoperative percutaneous transluminal angioplasty and endovascular stents, the tests for heterogeneity revealed that it had the significant heterogeneity (χ2=15.821, P 0.05), which indicated that the diameter stenosis and blocking rate of postoperative endovascular stents and percutaneous transluminal angioplasty in short-and medium-term had no significant differences. Conclusions Endovascular stents have advantages of a high success rate, higher safety and minimal invasion with definite efficacy in treatment of hepatic vein type Budd-Chiari syndrome. The diameter stenosis and blocking rate of postoperative endovascular stents and percutaneous transluminal angioplasty in short-and medium-term had no significant differences. For patients with unclear therapeutic effects in percutaneous transluminal angioplasty or with repeated percutaneous transluminal angioplasty, they may consider the endovascular stent therapy. Key words: Budd-Chiari syndrome; Hepatic vein occlusion; Interventional treatment; Endovascular stent