Abstract
Objective To study the application value of squamous cell carcinoma antigen(SCCAg) and HPV genotyping detection in diagnosis of cervical cancer.Method SCC-Ag and HPV were detected in 517 cases of CIN,63 cases of cervical cancer and 20 cases of healthy people.Results It took SCCAg ≥ 1.5 ng/ml as the cut-off.The positive rate in CIN group was 4.45％,while that in cervical cancer group was 66.67％.The positive rate of HPV-DNA in CIN group was 4.26％,while that in cervical cancer group was 96.83％.The sensitivity,specificity and accuracy rate of HPV-DNA were 96.83％,95.90％ and 96.00％; those of SCC-Ag were 66.67％,95.72％ and 92.67％; those of joint detection were 87.30％,99.44％ and 98.17％.Conclusions SCC-Ag can improve the accuracy rate of cervical cancer in HPV-DNA positive cases.The combination of SCC-Ag and HPV-DNA has important clinical significance in diagnosis of cervical cancer. Key words: HPV infection; SCC-Ag; Cervical cancer
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
