Abstract
Objective To study the clinical characteristics of the perioperative cognitive dysfunction in brain tumor patients. Methods One hundred and forty cases of brain tumor patients were evaluated by using the Chinese vesion of Montreal Cognitive Assessment Questionnaire before and after surgery. The distribution and clinical features of cognitive dysfunction in different located lesions and pathological types were analyzed and compared. Results Among the 140 brain tumor patients, the preoperative cognitive impairment and prevalence rate were 59.2%, the score was 24.2±2.4.The postoperative cognitive impairment and prevalence rate were 80.7%, the score was 20.5±4.1.The postoperative cognitive dysfunction prevalence was significantly higher than the preoperative in benign and malignant with infra or supratentorial brain tumor patients(80.0% vs 98.3%, 71.8% vs 92.2%, all P<0.05). Conclusions Vary different extent cognitive impairment was found in brain tumor patients in preoperative period. The postoperative cognitive dysfunction was seriously worse than that in the preoperative period in malignant and supratentorial brain tumors in earlier recovery period. Key words: Brain neoplasms; Cognitive disorders; Perioperative period
Published Version
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