THE CLINICAL AND MORPHOLOGICAL LESIONS OF THE ORAL MUCOSA AND PERIODONTIUM WITH VIRAL HEPATITIS C

Abstract

Background: Interest in the study of combined pathology has recently been explained by the accumulation of new facts, the emergence of new information about interorgan, intertissue and intercellular levels of interactionin the system of the whole organism. Studies of the oral cavity in chronic diffuse liver diseases are of great interest to clinicians, since pathological processes developing in the liver, as a rule, lead to organic and functional disorders in the oral mucosa. The aim of this study was to study the clinical and morphological lesions of the oral mucosa and periodontium in viral hepatitis C. Material and methods: 196 patients were examined, of which: the control group consisted of 100 patients with lesions of the oral mucosa (OM) and periodontal disease who were not diagnosed with HCV and 96 patients of the main study group. Dental status was studied. A pathological examination was carried out. Results: HCV patients group included 96 (63.5% males) and non-HCV group - 100 subjects (62.0% males) with lesions of oral mucous membrane. The lesions of lips and oral mucosa were more frequent in HCV than in the non-HCV group – e.g. erosion (13.5% vs 1%), cracks in the mouth corners (42.7% vs 0%), changes of oral mucosa surface (89.6% vs 3.0%), hemorrhages - (78.1% vs 0%) etc. Conclusion: Thus, during the clinical examination of patients with HCV, the average severity of periodontal damage prevailed. Numerous morphological features can be divided into those that are indicators of the severity and activity of inflammation.