Abstract
Actuality. In the treatment of erosive-ulcerative lesions of oral mucous membrane, caused by chronic mechanical trauma, it is reasonable to use the agents of complex action which would produce a local anti-inflammatory effect and reduce mucosal pain, and would have antiseptic and antimicrobial properties. One of them is Tantum Verde®, a local non-steroidal drug based on benzidamine hydrochloride.The aim of the research was to evaluate the effectiveness of the use of the preparation «Tantum Verde®» in the local treatment of erosive-ulcerative lesions of the oral mucous membrane caused by chronic mechanical trauma.Results of the research. There were treated 30 patients aged 18–58 with erosive-ulcerative lesions of oral mucous membrane, caused by chronic mechanical trauma of orthopedic structures or orthodontic devices. It was noted that 6 patients with removable prostheses had the growth of mucous membrane in areas of contact with the edges of the prosthesis. Among 15 patients from the experimental group, the preparation «Tantum Verde®» was additionally used. Absence or significant reduction of clinical signs of erosive-ulcerative lesions caused by mechanical trauma of orthopedic structures or orthodontic devices occurred 1–1,5 days earlier among the patients of experimental group. It is noted the positive effect of Tantum Verde® on pain reduction, hygienic condition, improvement of tissue trofics and healing of mucous membrane areas after surgical removal of prosthetic granulomas.Conclusions. The preparation «Tantum Verde®» is an effective painkiller that accelerates the disappearance of inflammatory signs, improves trophics, accelerates healing and epithelization of defects at patients with erosive-ulcerative lesions of oral mucous membrane, caused by chronic mechanical trauma with dental prostheses and non-removable orthodontic devices. It weakens the reactive inflammatory reaction of tissues to surgery after prosthetic granulomas removal, improves hygiene, accelerates healing and suture removal for 1–1,5 days.Keywords: «Tantum Verde®», chronic mechanical trauma of oral mucous membrane, erosive-ulcerative lesions, local treatment.
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