The Characteristic, Antibacterial Activities, and Hydrogel Formulation of Nanosilver Biosynthesis using Curcuma longa L. Juice

Abstract

Turmeric juice contains of aldehyde groups as bioreductor. Silver ion can be done as nanosilver by green synthesis method using plant extracts. Biosynthesis nanosilver can induce the antibacterial activity. Nanosilver then developed for topical product to treat acnes. The aims of this study are to determine the characteristics and antibacterial activity of nanosilver and the effect of it is concentration on the physical and chemical properties of gel. Nanosilver biosynthesis was prepared by mixing turmeric juice and AgNO3 solution for 24 hours at 25 ºC, then analyzed. Gel is made in variations concentration of nanosilver. Gel was evaluated including pH, viscosity, and dispersibility test during storage for 12 days at 25 ºC. Nanosilver biosynthesis with ratio of 5:38 mL was the best formula with absorption peak at 407 nm, round shape, particle size of 17.96 nm, and has broad spectrum antibacterial activity with strong category. FTIR spectra showed exist of interaction with spesific peaks. The concentration of nanosilver can affect to physical and chemical properties of gel, but all formulas meet the requirements and did not significantly change during 12 days at 25 ºC.