Abstract

Objective To observe perioperative change of thyroid hormone level and evaluate its prognostic significance. Methods The concentration of thyroid hormone was detected and compared with liver function and survival in 82 patients receiving liver transplantation. Results Preoperatively, the concentration of TT3 and TT4 in patients receiving liver transplantation was significantly lower than in control group. The concentration of TT3 and TT4 was decreased significantly when liver func-tion got worse. Thyroid hormone level of 72 recipients recovered to normal, and 7 patients died among these patients with the mortality being 9.7%. Thyroid hormone level of 10 patients didn't recover and 5 died with the mortality being 50% (P<0.05). Conclusion The decrease of TT3 and TT4 levels in patients receiving liver transplantation was correlated with worse liver function, and TT3 and TT4 level could be used to predict the prognosis. Key words: Liver transplantation; Thyroid hormones; Prognosis

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