Abstract
Patients with systemic lupus erythematosus (SLE) have such clinical manifestations as multiple thrombosis, PE, CNS diseases, livedo reticularis, labile hypertension, and habitual miscarriage. SLE affects people of all races, men and women, but in the latter it is dominant and especially often develops in women of reproductive age. Currently, it is generally recognized that such gestational complications as habitual abortion, preeclampsia and eclampsia, premature placental abruption, DIC and HELLP syndromes, thrombosis, fetal growth retardation, stillbirth, are associated with autoimmune diseases in the mother. The mechanism by which SLE aggravates the course of pregnancy and worsens its outcomes for the mother, fetus, and newborn remains undeciphered.
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