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PDF Availablehttps://doi.org/10.1136/jitc-2021-004475
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Cite Journal: Journal for ImmunoTherapy of Cancer |  Publication Date: May 1, 2022 |
 Citations: 87 |  License type: open-access |
Affiliation: German Cancer Research Center, Ludwig-Maximilians-Universität München, LMU Klinikum, Heidelberg University, University of South Florida, University Children's Hospital Tübingen, Vall d'Hebron Institute of Oncology, Moffitt Cancer Center, University of Erlangen-Nuremberg, Freie Universität Berlin, Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Miami Transplant Institute, Zimmer Biomet (Germany)
BackgroundCD19-directed chimeric antigen receptor T-cell therapy (CAR-T) represents a promising treatment modality for an increasing number of B-cell malignancies. However, prolonged cytopenias and infections substantially contribute to the toxicity burden...
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