The Biology and Pathology of Innate Immunity Mechanisms

Abstract

Preface. I: Pattern Recognition, Receptors and Collectins in Innate Immunity. 1. Mannose receptor and scavenger receptor: two macrophage pattern recognition receptors with diverse functions in tissue homeostasis and host defense S.A. Linehan, et al. 2. Complement receptor 3 (CR3): a public transducer of innate immunity signals in macrophages E. Yefenof. 3. The role of C-type lectins in the innate immunity against pulmonary pathogens I. Ofek, et al. 4. Modulation of nitric oxide production by lung surfactant in alveolar macrophages M. Kalina, et al. 5. Development of chimeric collectins with enhanced activity against influenza A virus K. Hartshorn, et al. 6. Initial steps in Streptococcus pneumoniae interaction with and pathogenicity to the host M. Shani-Sekler, et al. II: Host Cells and Cytokines in Innate Immunity. 7. Role of cytokines in the maturation and function of macrophages: effect of GM-CSF and IL-4 Y. Keisari, et al. 8. Mast cell modulation of the innate immune response to enterobacterial infection S.N. Abraham, R. Malaviya. 9. The NADPH oxidase diaphorase activity in permeabilized human neutrophils and granulocytic like PLB-985 cells I. Pessach, R. Levy. 10. Activation of cytosolic phospholipase A2 by opsonized zymosan in human neutrophils requires both ERK and p38 MAP-kinase I. Hazan-Halevy, R. Levy. 11. Cytosolic phospholipase A2 is required for the activation of the NADPH oxidase associated H+ channel in phagocyte-like cells R. Levy, et al. 12. The role of NK cells in innate immunity N. Lieberman, O. Mandelboim. 13. Similarities and dissimilarities between humans and mice looking at adhesion molecules efects A. Etzioni, et al. 14. The role of dendritic cells at the early stages of Leishmania infection H. Moll. 15. DNA-based vaccines: role of dendritic cells in antigen presentation L. Paul, A. Porgador. 16. Distinct patterns of IL-1a and IL-1b organ distribution -- a possible basis for organ mechanisms of innate immunity M. Hacham, et al. III: Antimicrobial Peptides. 17. Structure and biology of cathelicidins M. Zanetti, et al. 18. Structure activity relationship study of polymyxin B nonapeptide H. Tsubery, et al. IV: Innate Immunity in the Compromised Host. 19. The clinical significance of neutrophil dysfunction B. Wolach, et al. 20. Clinical significance of function aberrations in macrophages and NK cells, in type-1 cytokines and in lectin-binding molecules Z. Handzel. 21. Klebsiella infections in the immunocompromised host H. Sahly, et al. V: Innate Immunity Components in Cancer. 22. Macrophage -- recognized molecules of apoptotic cells are expressed at higher level in AKR lymphoma of aged as compared to young mice O. Itzhaki, et al. 23. Sensitivity to macrophages decreases with tumor progression in the AKR lymphoma T. Kaptzan, et al. 24. Opposing effects of IL-1a and IL-1b on malignancy patterns tumor cell-associated IL-1a potentiates anti-tumor immune responses and tumor regression, whereas IL-1b potentiates invasiveness R.N. Apte, et al.<