Abstract
To summarize the Bayesian model of the brain as it has been applied to hyper-salient experiences in psychosis such as ideas of reference (in particular, the attribution of personal meaning to the glance of strangers) and to amend this model by adding a Meaning Salience factor to the Bayesian equation that specifies the personal significance of the hyper-salient experience to the individual. Recent descriptions of the semi-independent processes of biological and psychological recovery from psychosis do not include an account of the figurative, metaphorical meaning of anomalous experiences in psychosis as seen from a psychoanalytic perspective. This review adds a psychodynamic factor to Bayesian brain function in psychosis. Personal meaning embedded in a delusion expressive of an individual’s life history may help explain the persistence of the ideational content of a delusion despite appropriate pharmacological treatment.
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