Abstract

<h3>Objective:</h3> To determine the effects of WVE-004 on <i>C9orf72</i> G<sub>4</sub>C<sub>2</sub> repeat-containing transcripts, DPR proteins, and C9orf72 protein levels. <h3>Background:</h3> A large <i>G</i><i><sub>4</sub></i><i>C</i><i><sub>2</sub></i><i> repeat expansion</i> in the <i>C9orf72</i> gene is the...

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Similar Papers

Paper Title
Journal
Date
Author
Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
Bahram Khosravi ... Thomas Arzberger
The EMBO Journal | VOL. 39
Bahram Khosravi, et. al.Bahram Khosravi ... Thomas Arzberger
16 Mar 2020
Retraction Note to: A new inducible transgenic mouse model for C9orf72-associated GGGGCC repeat expansion supports a gain-of-function mechanism in C9orf72-associated ALS and FTD.
Renate K Hukema ... Alex Maas
Acta Neuropathologica Communications | VOL. 4
Renate K Hukema, et. al.Renate K Hukema ... Alex Maas
01 Dec 2016
A new inducible transgenic mouse model for C9orf72-associated GGGGCC repeat expansion supports a gain-of-function mechanism in C9orf72-associated ALS and FTD.
Renate K Hukema ... Lies-Anne Wfm Severijnen
Acta Neuropathologica Communications | VOL. 2
Renate K Hukema, et. al.Renate K Hukema ... Lies-Anne Wfm Severijnen
01 Dec 2014
Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.
Qihui Zhou ... Carina Lehmer
EMBO Molecular Medicine | VOL. 9
Qihui Zhou, et. al.Qihui Zhou ... Carina Lehmer
28 Mar 2017
View more papers

More From: BMJ : British Medical Journal

Paper Title
Journal
Date
Author
University of Toronto researcher resigns over “systematic” data fraud
O Dyer
BMJ : British Medical Journal | VOL. 351
O DyerO Dyer
12 Nov 2015
Pelvic pain
R Brown ... S Vyas
BMJ : British Medical Journal | VOL. 351
R Brown, et. al.R Brown ... S Vyas
12 Nov 2015
Building on good data foundations
T Bloom
BMJ : British Medical Journal | VOL. 351
T BloomT Bloom
12 Nov 2015
Social media could provide early warning of virus outbreaks
N Hawkes
BMJ : British Medical Journal | VOL. 351
N HawkesN Hawkes
12 Nov 2015
View more papers

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.