The avoiding late diagnosis of ovarian cancer (ALDO) project; a pilot national surveillance programme for women with pathogenic germline variants in BRCA1 and BRCA2

Sue Philpott ,Steve Skates ,Helen Hanson ,D Gareth Evans ,Malcolm Scott ,Janos Balega ,Anjana Kulkarni ,Angela Brady ,Katie Snape ,Maria Raikou ,Kevin J Hayes ,Ranjit Manchanda ,Athena Lamnisos ,Joyce S Solomons ,Michelle Lockley ,Alistair Mcguire ,Louise Izatt ,Emma R Woodward ,Vishakha Tripathi ,Maghfoor Ahmed ,Aarti Sharma ,Julian Adlard ,Lucy Side ,Richard Edmondson ,Adam N Rosenthal

doi:10.1136/jmg-2022-108741

The avoiding late diagnosis of ovarian cancer (ALDO) project; a pilot national surveillance programme for women with pathogenic germline variants in BRCA1 and BRCA2

Sue Philpott , Steve Skates + Show 23 more

Open Access

https://doi.org/10.1136/jmg-2022-108741

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Journal: Journal of Medical Genetics	Publication Date: Nov 1, 2022
Citations: 9	License type: open-access

#Risk-reducing Bilateral Salpingo-oophorectomy #Risk Of Ovarian Cancer Algorithm + Show 8 more

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Abstract

BackgroundOur study aimed to establish ‘real-world’ performance and cost-effectiveness of ovarian cancer (OC) surveillance in women with pathogenic germline BRCA1/2 variants who defer risk-reducing bilateral salpingo-oophorectomy (RRSO).MethodsOur study recruited 875...

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