Abstract
Krouwer (1) makes a valid point that total error for a measurement procedure must include analytical nonspecificity influences (referred to as “random patient interferences” by Krouwer) as well as mean calibration bias and imprecision components. Fig. 3 in the report from the Laboratory Working Group (LWG) of the National Kidney Disease Education Program showed boundaries for combinations of bias and imprecision that would contribute no more than a 10% change in root mean square error for estimates of glomerular filtration rate …
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