Abstract

This article deals with the epidemiological datashowing higher frequency of arterial hypertension (AH) in patients with ischemic heart disease (IHD). We discussed the basic characteristics of modern domestic and foreign recommendations for treating patients with combination of AH and IHD. We showed the target of blood pressure (BP) in this category of patients. This article deals with the priority groups of antihypertensive drugs, which have the advantages in the combination usage in patients with association of these diseases. We fixed special attention to the problem of BP variability (BPV) as a new risk factor for the development of coronary complications in patients with AH. We showed the possibility of fixed combination of perindopril and amlodipine in reducing interand intervisit BPV in patients with AH and IHD in actual clinical practice.

Highlights

  • The association of arterial hypertension and ischemic heart disease is the main problem in modern cardiology practice

  • We showed the target of blood pressure (BP) in this category of patients

  • We showed the possibility of fixed combination of perindopril and amlodipine in reducing inter- and intervisit BP variability (BPV) in patients with arterial hypertension (AH) and ischemic heart disease (IHD) in actual clinical practice

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Summary

Introduction

The association of arterial hypertension and ischemic heart disease is the main problem in modern cardiology practice. Результаты рандомизированных клинических исследований по АГТ не выявили убедительных доказательств, что целевое САД у больных АГ с клинически манифестной ИБС должно быть на уровне менее 130 мм рт. Именно поэтому в настоящее время рекомендуемый уровень САД для лиц с АГ и ИБС – менее 140 мм рт.

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