The Association between Muscle Strength and Hyperuricemia in the Healthy Middle-aged Adult in Yangpyeong Province

Abstract

Purpose: This study aimed to examine the prevalence of hyperuricemia in association with relative grip strength and leg strength in Korean Elderly. Methods: We studied cross-sectional analysis with 1,894 rural adults (40-88 years old), who were surveyed for 7 years from 2007 to 2014. Grip strength was measured by using Takei grip strength dynamometer. Leg strength was measured by using Takei leg strength dynamometer. Hyperuricemia was defined by examining serum uric acid concentration (male ≥7 mg/dL, female ≥6 mg/dL). Logistic regression was conducted to evaluate the association of grip strength and leg strength with hyperuricemia (p＜0.05). Results: Subjects who reported high level of relative grip strength had a significantly lower odds ratio (OR) of hyperuricemia than subjects who reported low level of relative grip strength (OR, 0.37; 95% confidence interval [CI], 0.16-0.84). When it comes to sex, subjects both high relative muscle strength are significantly lower multivariate-adjusted OR of hyperuricemia than subjects both low relative muscle strength in male (OR, 0.52; 95% CI, 0.29-0.95) and female (OR, 0.47; 95% CI, 0.26-0.95). Additionally, senior group (age ≥65 years), who have low relative grip strength and high relative leg strength, was only significantly associated with the prevalence of hyperuricemia (OR, 0.43; 95% CI, 0.19-0.98).