Abstract
Results The study population included 49 (47.6%) males and 54 (52.4%) females with a mean age of 7.6 ± 1.6 years. The advanced bone age group defined as BA-CA>1 year (n=53) had significantly higher HOMA-IR, fasting insulin levels and lower quantitative insulin sensitivity check index (QUICKI). Also, BA-CA was significantly correlated with fasting insulin (r=0.315, P<0.001), HOMA-IR (r=0.288, P<0.001), and QUICKI (r=-0.353, P<0.001). In multiple regression analysis, fasting insulin was identified as significant independent predictors for BA-CA.
Highlights
Obesity is associated with bone age (BA) advancement of unclear etiology
Our objective was to investigate the association with BA maturation and insulin levels in children with overweight and obesity
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Summary
The association between bone age advancement and insulin in prepubertal children with obesity. From 8th APPES Biennial Scientific Meeting Darwin, Australia. Aims Obesity is associated with bone age (BA) advancement of unclear etiology. Our objective was to investigate the association with BA maturation and insulin levels in children with overweight and obesity. Doi:10.1186/1687-9856-2015-S1-P71 Cite this article as: Lee et al.: The association between bone age advancement and insulin in prepubertal children with obesity. International Journal of Pediatric Endocrinology 2015 2015(Suppl 1):P71
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