Abstract
The construction of oral mucosa infection model in vitro is conducive to exploring the pathogenesis and prevention strategies of oral infectious diseases of oral mucosa. The organotypic oral mucosal infection model is based on the tissue-engineered oral mucosa, which is cocultured with the extraction of pathogens, planktonic microorganisms, biofilm or saliva, to mimic the interactions between the oral microbiome and the oral mucosa of the host. In recent years, researchers have used this technology to study the role of microbes in the development and pathogenesis of oral mucosal diseases and periodontal diseases. This article reviews the construction, recent advances and perspectives of the organotypic oral mucosa infection model. Key words: Tissue engineering; Biofilms; Mouth mucosa; Infection; Three-dimensional cultures
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
