Oral Biofilms and bone resorption

Abstract

A lot of oral diseases, including marginal periodontitis, are infectious diseases that caused by the oral biofilm-forming bacteria for example dental biofilm (dental plaque). The oral biofilm is paid to attention as a risk factor of the systemic disease such as metabolic syndrome, osteoporosis, aspiration pneumonia, diabetics, and the infective endocarditises. It had been shown that 500 bacterial species inhabited with symbiosis and antagonization within the oral biofilm and communication among bacteria is essential for initial colonization and subsequent biofilm formation on human teeth and oral mucosa. The feature and the realities of the biofilm to cause the bone absorption were outlined in this manuscript and speculated how the biofilm-forming bacteria approach to the alveolar bone, although it was difficult to clarify the whole contents of human oral biofilm that presented a various aspect.