The application value of SonoLiver software in differential diagnosis of the nodules within prostatic inner gland

Abstract

Objective To provide objective basis for the diagnosis on nodules of prostatic inner gland by SonoLiver software with the dynamic vascular pattern (DVP) and the parameters of contrast-enhanced ultrasonography(CEUS). Methods In a reprospective study, CEUS was performed in 104 cases with nodules of prostatic inner gland that were divided into four groups including the benign prostatic hypertrophy(BPH) group (n=26) and prostate cancer(PCa) group (n=29), the others in high grade prostate intraepithelial neoplasia(HGPIN, n=25) and low grade prostate intraepithelial neoplasia(LGPIN, n=24) that developed from BPH. The SonoLiver software was used to analyze the CEUS of nodules to get the DVP and parameters of CEUS. Results Among the four groups, the prostate specific antigen (PSA) level and nodule maximal size were significant different(P 0.05). The nodules in BPH and LGPIN group mostly were cold-warm colour, also as only cold colour(P>0.05). The difference of DVP among the four groups was significant (P<0.05). Conclusions The application of SonoLiver software with DVP and parameters of CEUS is valuable to diagnose the nodules of prostatic inner gland. Key words: Contrast-enhanced ultrasound; Prostatic neoplasms; Diagnosis; Dynamic vascular pattern