The application of MRI imaging in assessing the curative effect of neoadjuvant chemotherapy in breast cancer

Abstract

Objective To observe the consistency of MRI imaging and pathological examination.To discuss the value of MRI imaging in assessing the curative effect of neoadjuvant chemotherapy in breast cancer. Methods 98 patients with breast cancer were selected as research subjects.All patients received six cycles of neoadjuvant chemotherapy, and underwent surgical treatment after the end of chemotherapy.All of them were performed with MRI examination before and after 6 cycles of chemotherapy.The evaluation of MRI in assessing the neoadjuvant chemotherapy and postoperative efficacy of breast cancer were compared for the consistency. Results The total effective rate by pathological examination of 98 cases of breast cancer after 6 cycles of neoadjuvant chemotherapy was 71.4%, and the effective rate by MRI examination was 74.5%, and two evaluation results were basically consistent.The sensitivity, specificity and accuracy of MRI to assess the complete response (CR) patients after chemotherapy were 87.3%, 67.1% and 78.2%, respectively, which of the partial response(PR) patients were 92.5%, 59.7% and 85.9%, respectively.The tumor shrinkage of 22 patients was reduced towards the heart, with 23 branches reduced according to the MRI image.The average gap between MRI measured maximum tumor diameter and pathological examination results was (0.42±0.27)cm. Conclusion The evaluation of MRI in assessing the neoadjuvant chemotherapy was consistent with the pathology results, which could be used for clinical treatment and surgery program, worthy of clinical application. Key words: Magnetic resonance imaging; Chemotherapy, adjuvant; Breast neoplasms