The Application and Mechanism Exploration of N-Butylphthalide in the Treatment of Carbon Monoxide Poisoning

Abstract

This study comprehensively explored the application and the mechanism of action of N-Butylphthalide (NBP) in the treatment of carbon monoxide (CO) poisoning. The article begins with an overview of the physiological impacts of CO poisoning, particularly highlighting its inhibition of blood oxygenation function and its extensive damage to the nervous system. Subsequently, the paper delves into the pharmacological characteristics of NBP, discussing its potential role in neuroprotection, and supports the application value of NBP in the treatment of CO poisoning with animal experiments and preliminary clinical data. Although current research results have preliminarily confirmed the neuroprotective effects of NBP, key parameters such as the specific dosage, therapeutic time window, and long-term safety in the treatment of CO poisoning still require further investigation and clarification. The paper concludes with a proposal for future studies to deepen the understanding of the mechanism of action of NBP, explore its synergistic effects with existing treatments, and validate its efficacy and safety in the treatment of CO poisoning through extensive clinical trials. In summary, as an emerging neuroprotective agent, NBP shows significant potential in the field of CO poisoning treatment, and it is hoped that future research will provide more effective and safe treatment options for patients with CO poisoning.