Abstract
Alkali-soluble and ether-soluble complement-fixing antigens were isolated by chemical fractionation of purified psittacosis and feline pneumonitis elementary body suspensions disrupted by sonic vibration. Both group- and species-specific serological activity were demonstrated in the alkali-soluble fractions by means of cross absorption and cross complement fixation tests. The destruction of the group activity with either potassium periodate or lecithinase produced psittacosis and feline pneumonitis species-specific antigens. In comparable experiments, the ether-soluble antigens exhibited only group serological activity. The alkali-soluble and ether-soluble group-specific complement-fixing antigens are serologically related. However, they show differences in heat stability, hemagglutinating properties, and prozone manifestation.
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