Abstract
Abstract Skin test antigens prepared from phenol-treated suspensions of yolk sacs of embryonated eggs infected with lymphogranuloma venereum, meningopneumonitis, ornithosis, feline pneumonitis, psittacosis, or mouse pneumonitis virus all elicited positive reactions when titrated in L.V. patients. The dermal activity of certain of the heterologous viruses, shown in the titrations, was slightly less than that of the homologous L.V. virus, suggesting slight species-specificity among these agents. However, the difference was neither great enough nor sufficiently consistent to be of practical significance in providing a species-specific diagnosis in infection with these agents. It is suggested that the mouse pneumonitis or feline pneumonitis viruses, which are nonpathogenic for man, might be profitably substituted for the highly virulent L.V. virus presently used to prepare skin test antigen.
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