The Antibacterial Effects of Healing Abutments Coated with Gelatin-curcumin Nanocomposite.

Abstract

For the long-term success of implant treatment, prevention of biological complications, including pre-implant diseases, plays an important role. The use of antimicrobial coatings is one of the prosperous methods in this field. The aim of this study is to evaluate the antimicrobial effects of healing abutments coated with gelatin-curcumin nanocomposite. This study included 48 healing abutments in the form of a control group (titanium healing abutments without coating) and an intervention group (titanium healing abutments coated with gelatin-curcumin nanocomposite). The disc diffusion method was used to evaluate the antimicrobial effects of coated healing abutments against Escherichia coli, Staphylococcus aureus and Enterococcus faecalis and the results were reported in a non-growth zone area. Gelatin-curcumin nanocomposite caused significant non-growth aura for all three bacteria compared to the control group. For the control group (healing abutments without coating), the antimicrobial effects (non-growth zone) were zero. Besides, gelatin-curcumin nanocomposite had the greatest inhibiting effect on the growth of S. aureus, then E. coli and finally E. faecalis. The results of our study showed that the coating used was able to significantly demonstrate a non-growth zone against all three bacteria compared to the control group without coating. Further evaluations in various physicochemical, mechanical, and antimicrobial fields are necessary for the animal model and clinical phase.