The analysis of distribution and drug resistance of pathogens in mild degree burn patients after systemic antibacterial therapy

Abstract

Objective To investigate the distribution and drug resistance of pathogen isolated from mild degree burn patients after systemic antibacterial therapy. Methods From January 2014 to December 2017, outpatients with mild degree burn in our hospital were selected, and were divided into two groups according to whether accepting systemic antibacterial therapy or not. The pathogens cultured from the wound of the burn patients were identified by the ATB Expression semi-automatic bacteria identification system of Biomerieux France. The bacterial identification was carried out according to National Clinical Laboratory Operation Guidelines. All of the data were statistically analyzed by the SPSS19.0 software. Results There was no statistically significant difference in the rate of appearance of pathogens between the two groups. The percentage of gram-positive was 83.1% in systemic antibacterial therapy group, 86.4% in non systemic antibacterial therapy group. The strains of drug resistant gram-positive bacteria in systemic antibacterial therapy group were more than another group, there was no statistically significant difference in drug resistant gram-negative bacteria between the two groups. Conclusion Systemic antibacterial therapy can’t lower the infection rate of burn wound in mild burn patients, but it can increase the number of strains of drug resistant gram-positive bacteria. Key words: Systemic antibacterial therapy; Mild degree burn; Pathogen