Abstract
Parenteral nutrition associated cholestasis (PNAC) is a complication of premature infants caused by multiple factors and directly related to parenteral nutrition, resulting in multiple organ dysfunctions in premature infants.Long-term parenteral nutrition and intestinal failure are the main risk factors of PNAC.Its mechanism is complicated, and there is no effective prevention and control measures at present.This article mainly reviews the pathogenesis, risk factors and application of fish oil in PNAC. Key words: Cholestasis; Premature infant; Parenteral nutrition; Phytosterol; Fish oil
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