Abstract
BackgroundBreast cancer is a major health problem resulting in high morbidity and mortality. Early diagnosis of primary and secondary lesions is crucial to optimize treatment options. Our study aimed to investigate the role of PET-CT and CT alone in detecting metastatic lesions in breast cancer patients.ResultThis retrospective study showed better PET diagnostic performance in the detection of lymph nodal and lytic bony metastatic deposits with more accurate detection of the malignant nature of hepatic focal lesions and detection of activity in sclerotic bony lesions, compared with CT alone, while CT had a higher value in the localization of lesions. Hybrid PET/CT showed optimal diagnostic performance than each modality separately.ConclusionThe combination of CT and PET was a powerful diagnostic tool that is more accurate than CT alone in the detection of distant metastases.
Highlights
IntroductionDiagnosis of primary and secondary lesions is crucial to optimize treatment options
Breast cancer is a major health problem resulting in high morbidity and mortality
The combination of computed tomography (CT) and Positron emission tomography (PET) was a powerful diagnostic tool that is more accurate than CT alone in the detection of distant metastases
Summary
Diagnosis of primary and secondary lesions is crucial to optimize treatment options. Our study aimed to investigate the role of PET-CT and CT alone in detecting metastatic lesions in breast cancer patients. Breast cancer is the most common cancer among females It is the primary cause of cancer-related death among females globally, with an estimated 627,000 deaths in 2018 [1]. Spread to axillary lymph nodes or distant metastasis may be encountered in patients recently diagnosed with breast cancer [2]. The distant metastatic breast cancer represents the most severe form of the disease [3]. Early and accurate detection of secondary lesions is crucial to optimize treatment approaches helping in improving long-term survival rates and quality of life [4].
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