Abstract

BackgroundPeriprosthetic joint infection (PJI) is a devastating complication following total joint arthroplasty (TJA). Now, the definition of PJI traditionally used in clinical practice was set out by the International Consensus Meeting (ICM) and Infectious Diseases Society (IDSA). There was a new definition proposed in May 2018 on a paper published in the Journal of Arthroplasty. The new scoring system for PJI demonstrated a higher sensitivity and specificity than Musculoskeletal Infection Society and IDSA criteria. Therefore, we wanted to find further evidence to support the new definition in the Chinese population.MethodsThe patients who were included in our study were divided into PJI group and aseptic group. Medical records of patients (98 in PJI group and 165 in aseptic group) were reviewed, and the score of every patient was aggregated based on the new definition and collected data. The sensitivity and specificity were compared between new definition and classical criteria.ResultsFor patients in our hospital, the overall sensitivity and specificity of the new criteria were respectively 94.9% (95% confidence interval [CI] 87.9–98.1%) and 95.2% (95% CI 90.3–97.7%). The new definition demonstrated a higher sensitivity than traditional criteria in Chinese population, and the specificity was similar to existing criteria.ConclusionWe believe the new scoring system about periprosthetic joint infection could also apply to Chinese population for diagnosing PJI following TJA. It can obviously improve diagnostic efficiency for PJI compared with traditional criteria.

Highlights

  • Periprosthetic joint infection (PJI) is the most serious complication that lowers the quality of patients’ life by elevating the patients’ burden of cost and affecting the outcome of total joint arthroplasty (TJA) [1,2,3]

  • The positive predictive value (PV+) and negative predictive value (PV−) of the new criteria were respectively 92.1% and 96.9% (95% [confidence intervals (CI)] 92.6–98.9%). (Table 3)

  • In conclusion, the 2018 new scoring system put forward by researchers could apply to the Chinese population for diagnosing PJI following THA or Total knee arthroplasty (TKA)

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Summary

Introduction

Periprosthetic joint infection (PJI) is the most serious complication that lowers the quality of patients’ life by elevating the patients’ burden of cost and affecting the outcome of total joint arthroplasty (TJA) [1,2,3]. Researchers evaluated serum markers, synovial markers, and intraoperative findings and proposed an evidence-based, weightadjusted scoring system for definition of PJI in hip and knee in 2018 [13]. Periprosthetic joint infection (PJI) is a devastating complication following total joint arthroplasty (TJA). The definition of PJI traditionally used in clinical practice was set out by the International Consensus Meeting (ICM) and Infectious Diseases Society (IDSA). The new scoring system for PJI demonstrated a higher sensitivity and specificity than Musculoskeletal Infection Society and IDSA criteria. We wanted to find further evidence to support the new definition in the Chinese population

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