Abstract

When funding for Tetrahymena Genome Database (TGD) ended in 2006, no further updates were made to this important community resource and the main database was taken offline in 2008. We have restored and updated this important resource for use by the Tetrahymena research community. We have also retooled the TGD website (now TGD Wiki) to allow members of the community to directly update the information presented for each gene, including gene names, descriptions and Gene Ontology annotations, from a web browser. Maintenance of genome annotations by the authors generating and publishing primary data, rather than dedicated scientific curators, is a viable alternative for the upkeep of genomes, particularly for organisms with smaller research communities. By combining simple, intuitive displays with the powerful search functions made possible by its underlying relational database, TGD Wiki has been designed to maximize participation by bench scientists in the development of their community bioinformatics resource.Database URL: http://ciliate.org

Highlights

  • The genome of the ciliated protozoan Tetrahymena thermophila was sequenced at The Institute for Genomic Research (TIGR) in 2003 [1]

  • From 2004 to 2009, Tetrahymena Genome Database (TGD; http://www.ciliate. org) was housed at Stanford University, where it served as the primary portal to genomic information about this organism

  • TGD was modeled after Saccharomyces Genome Database (SGD), employing a nearly identical schema and interface to this successful model organism database (MOD) [3]

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Summary

Original article

Tetrahymena genome database Wiki: a community-maintained model organism database. When funding for Tetrahymena Genome Database (TGD) ended in 2006, no further updates were made to this important community resource and the main database was taken offline in 2008. We have restored and updated this important resource for use by the Tetrahymena research community. We have retooled the TGD website ( TGD Wiki) to allow members of the community to directly update the information presented for each gene, including gene names, descriptions and Gene Ontology annotations, from a web browser. Intuitive displays with the powerful search functions made possible by its underlying relational database, TGD Wiki has been designed to maximize participation by bench scientists in the development of their community bioinformatics resource.

Introduction
Database construction
Website displays
Data types and sources
Plasmodium falciparum Saccharomyces cerevisiae Toxoplasma gondii
Future directions
Full Text
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