Abstract
Abstract We report herein structural characterization of monomeric platinum complexes of the composition: Pt(η4–P4L), Pt(η4–P3SiL), Pt(η4–P2N2L), Pt(η4–P2S2L), Pt(η4–P2C2L), Pt(η4–PN3L), and Pt(η4–PN2OL). The tetradentate ligands with 10-, 11-, 12-, 14-, and 16-membered macrocycles create a variety of chelate bond angles. A distorted square-planar geometry about Pt(II) atoms with cis–configuration by far prevail. There is an example Pt(η4–P3SiL) in which the respective donor atoms build up a trigonal-pyramidal geometry about Pt(II) atom.
Highlights
Organophosphines are amongst the most widely studied ligand systems, in part because of the ability to modify their steric and electronic properties
We report structural characterization of monomeric platinum complexes of the composition: Pt(η4–P4L), Pt(η4–P3SiL), Pt(η4–P2N2L), Pt(η4–P2S2L), Pt(η4–P2C2L), Pt(η4–PN3L), and Pt(η4 –PN2OL)
The chemistry of platinum is important in the areas of catalysis and biochemistry
Summary
Organophosphines are amongst the most widely studied ligand systems, in part because of the ability to modify their steric and electronic properties. Organophosphines as soft donor ligands are very attractive and useful in the platinum chemistry. A resurgence of interest in these apparently complexes of platinum started in 1969 when (Rosenberg et al, 1969) discovered the antitumor activity of cis-Pt(NH3)2Cl2 commonly known as „cisplatin“. This has included a considerable number of structural determinations which have helped to shed light on biological and other activity (Holloway and Melnik, 2002, 2003, 2004). There are four types of isomers, included are distortion (65%), cis-trans (30%), mixed isomers (cis-trans+distortion) and ligand isomerism. Distortion isomers, differing only by degree of distortion in Pt–L distances and L–Pt–L angles, are the most numerous
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