Abstract
Application of tritiated tetracycline by means of hydrophilic gel contact lenses in rabbits revealed that about 20% of the antibiotic was released from the gel during a contact time of 5 h. Abrasion of the epithelium increased the intraocular penetration considerably. No accumulation of tetracycline in the eye tissues was observed even after 72 h of continuous application of contact lenses presoaked in tetracycline. Compared with the instillation of tetracycline solution, the application of contact lenses presoaked in tetracycline is much more effective with respect to the achieved level of the antibiotic in the eye.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.