Testosterone Therapy of Male Eunuchoids

Abstract

IN A series of papers (1, 2, 3, 4) the principal author and several associates have contributed evidence establishing the clinical effectiveness of various testosterone compounds in the treatment of a highly specific endocrine deficiency, primary male hypogonadism or eunuchoidism. In successive reports the various modes of administering testosterone have been discussed and compared with regard to the convenience of dosage necessary for originating improvement and the maintenance of the benefits achieved. These publications included convincing photographic (before and after treatment) proof that the intramuscular injection of testosterone propionate, the implantation of methyl testosterone pellets, the peroral swallowing of methyl testosterone tablets and the sublingual absorption of testosterone compounds dissolved in propylene glycol—all were successful in correcting the severe genital retardation of primary hypogonadism. In the last paper of this group (4) testosterone propionate, methyl testosterone an...