Abstract
A Bacillus thuringiensis preparation used for microbial control of flies was tested for development of resistance to thuringiensin in Drosophila melanogaster. A 10-fold resistance developed in 30 generations in fruitflies reared in medium containing 0.3 to 1.0% preparation but did not rise from generations F 30 to F 70. A 6-fold resistance was obtained at 0.2 to 0.5% preparation. Flies reared in 2 and 3% preparation were very weak and did not develop resistance during selection. On the contrary, they died out in generation F 58. Tests with fruitflies resistant to chemicals have shown that there is no cross-resistance between chemicals and thuringiensin. These data are discussed relative to the use of thuringiensin in controlling flies.
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