Abstract
In discussing these 2 patterns, a detailed review has been made of the composition of plasma (in terms of water, proteins, crystalloids and lipids) and of the physico-chemical composition of proteins and lipids. This should enable the reader to give a clearer explanation to his clinical colleagues in instances of pseudohyponatremia from water 'displacement'. Prompt notification to the clinical of the laboratory observation that a specimen of plasma or serum is lipemic may on occasion prevent incorrect and potentially dangerous therapy of a 'low' sodium concentration or even, rarely, an unnecessary laparotomy for acute abdominal pain. It is for these very practical reasons that the examples have been chosen.
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