Содержание биоэлементов в плазме крови и тканях крыс в норме и после избыточного поступления кальция и магния с питьевой водой

Abstract

The article describes the effect of drinking water with a high content of vital calcium and magnesium cations on the ionic composition of Wistar rat tissues and blood plasma. Three groups of animals were studied: control animals on standard feed and water consumption (Ca2+ = 20 mg/dm3; Mg2+= 6 mg/dm3); and 2 experimental groups of animals that consumed water with an increased concentration of Ca2+ (120 mg/dm3) or Mg2+ (70 mg/dm3) for 7 weeks. The content of sodium, potassium, calcium, magnesium, aluminum, copper, iron, phosphorus, silicon, strontium and zinc in the tissues of liver, kidneys, skeletal muscles, bones, and subcutaneous fat tissue, as well as in blood plasma of laboratory animals was determined. Methods of atomic absorption spectrometry, biochemical analysis, and flame photometry were used to determine the studied parameters. In the group of animals consuming drinking water with a high concentration of calcium, an increase in the content of all the studied macro - and microelements, except copper, in the liver and subcutaneous fat was revealed. After excessive magnesium intake, there was an increase in the content of sodium, calcium, copper, iron, phosphorus, and zinc mainly in the skeletal muscle and liver. The level of macro-and microelements in the blood plasma of rats of both experimental groups did not differ from the normative values and between groups. The results deepen the understanding of the mineral composition of the body, its organs, and tissues in normal state and long-term consumption of drinking water with an excess of calcium and magnesium.