Abstract
Asymmetric mono - and dibromides aza-BODIPYs at 6-site were prepared. The singlet oxygen yield of monobromide MBr-azaBDP with the direct attachment of the –Br group at 6-site was higher than that of vinyl dibromide DBr-azaBDP. Self-assembled MBr-azaBDP-NPs with laser irradiation possessed a photothermal conversion capability. Monobromide MBr-azaBDP was discovered to be an effective PDT-PTT combined therapeutic agent and prospective candidate for tumor phototherapy by integrating tert-butyl free rotation and halogen substitution. However, comparing to MBr-azaBDP, DBr-azaBDP as a fluorescent dye possesses narrower full width at half maxima, higher molar extinction coefficient and fluorescence quantum yield.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
