Abstract

Tenofovir has shown efficacy as first-line therapy for treatment-naive patients with chronic hepatitis B virus (HBV) infection (JW Gastroenterol Jan 23 2009). To evaluate whether tenofovir is effective in treatment-experienced patients — those who failed to respond to nucleoside/nucleotide analogues (NAs) — European investigators conducted a multicenter, retrospective cohort study involving 131 HBV-monoinfected patients who failed …

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