Temporal correlation of fMRI and EEG with asymmetric fusion

Abstract

Event Abstract Back to Event Temporal correlation of fMRI and EEG with asymmetric fusion Adil Deniz A. Duru1*, Itır Kaşıkçı2, Elif Kurt3, Ahmet Ademoğlu4 and Tamer Demiralp5 1 Biomedical Eng. Inst, Türkiye 2 Neuroscience Dept. Institute of Experimental Medicine, Istanbul University, Türkiye 3 Experimental Medicine, Istanbul University, Türkiye 4 Biomedical Eng. Inst. Bogazici University, Türkiye 5 Istanbul Medical Faculty, Physiology Department, Istanbul University, Türkiye The relationship between the hemodynamic response and the electro-physiological activity of the brain is investigated non-invasively using fMRI and EEG measurements. Simultaneous recordings of these two modalities allow us to analyze the spatiotemporal correlation between the electrophysiological activities and the BOLD signal. We perform an asymmetric EEG-fMRI fusion on a voxel level by using the electrical and hemodynamic steady state visual responses of the brain. A bayesian source localization algorithm is used to project the sensor space EEG data into the source space in which the fMRI BOLD is directly measured. The EEG and fMRI data are spatio-temporally co-registered to obtain statistical parameter maps that show their temporal correlation on a spatial cortical manifold. Flashing light stimuli covering the alpha range at 6, 8, 10 and 12 Hz are presented to healthy subjects in a boxcar design consisting of 3 consecutive rest and stimulation periods and the EEG and fMRI data are simultaneously recorded. The statistical maps of correlations of hemodynamic responses with the source space EEG are determined. In general, a high positive correlation is obtained between the BOLD signal and the EEG power at the stimulation frequency and its harmonics, while at the same time the alpha band power of the EEG showed a significant negative correlation with the BOLD signal. This illustrates that even in a narrow frequency band of the EEG, the relationship between the EEG and fMRI responses contains multiple contrasting components that should be taken into consideration for a reliable EEG-fMRI fusion. Keywords: BOLD signal, Information Processing Conference: XI International Conference on Cognitive Neuroscience (ICON XI), Palma, Mallorca, Spain, 25 Sep - 29 Sep, 2011. Presentation Type: Poster Presentation Topic: Poster Sessions: Motor Information Processing Citation: Duru AA, Kaşıkçı I, Kurt E, Ademoğlu A and Demiralp T (2011). Temporal correlation of fMRI and EEG with asymmetric fusion. Conference Abstract: XI International Conference on Cognitive Neuroscience (ICON XI). doi: 10.3389/conf.fnhum.2011.207.00097 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 16 Nov 2011; Published Online: 25 Nov 2011. * Correspondence: Dr. Adil Deniz A Duru, Biomedical Eng. Inst, Istanbul, Türkiye, deniz.duru@boun.edu.tr Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Adil Deniz A Duru Itır Kaşıkçı Elif Kurt Ahmet Ademoğlu Tamer Demiralp Google Adil Deniz A Duru Itır Kaşıkçı Elif Kurt Ahmet Ademoğlu Tamer Demiralp Google Scholar Adil Deniz A Duru Itır Kaşıkçı Elif Kurt Ahmet Ademoğlu Tamer Demiralp PubMed Adil Deniz A Duru Itır Kaşıkçı Elif Kurt Ahmet Ademoğlu Tamer Demiralp Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.