Abstract
BackgroundSurface modified metallic implants with nanoporous morphology finds extensive application as functional implant material as it mimics the biological conditions as well as matches the mechanical characteristics of the bone. The current study involves synthesis of nano-titania coating by the employment of PMMA as a templating agent and compared with widely used PEG 400. MethodThe titania coatings were synthesized by sol-gel methodology and deposited on 316 L SS by dip coating method. The coating morphology was characterized by Attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-IR), X-ray diffraction analysis (XRD), Scanning electron microscopy - energy dispersive X-ray analysis (SEM-EDX) and Atomic force microscopy (AFM). The bioactive nature of the coatings were evaluated by in vitro bioactivity study in simulated body fluid (SBF). The toxicity and cell adhesion of the coatings were analyzed by MTT assay. The ability of the coatings to resist corrosion was studied with potentiodynamic polarization and electrochemical impedance spectroscopy. Significant findingsThe changes in the cell adhesion behavior are observed for the different coatings. The TiO2 coatings exhibited excellent corrosion resistance. Besides, the nanoporous coating developed with PMMA as the templating agent revealed excellent bioactivity as well as higher corrosion resistance.
Published Version
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