Abstract
In this study, temperature uniformity and heating rate of heat spreader with multi-well are simulated and analyzed by CFD software under natural convection condition. Firstly, multi-well heat spreader made of aluminum, copper, silver and vapor chamber are simulated and compared, when dual and six heat sources are applied at a heating power of 1200W. Secondly, with six heat sources at heating power of 188, 300, 600 and 1200W, the heating rate of heat spreaders are studied. Vapor chamber heat spreader has the better temperature uniformity both in six sources and dual sources mode due to a higher thermal conductivity, followed by silver, copper and aluminum heat spreader. Aluminum and silver heat spreader show the higher heating rate, followed by copper heat spreader, vapor chamber heat spreader due to a larger heat capacity, heat up the slowest.
Highlights
The polymerase chain reaction, PCR, was invented by K
The size of the multi-well heat spreader is four times that of a micro chip and utilizes the temperature uniformity of a vapor chamber heat spreader, which allows simultaneous operations, in order to meet the needs of PCR
The results show that copper fins have the obvious phenomena of centralizing the heat sources, which can generate a situation of uneven temperature; in contrast, a vapor chamber with copper fins has even temperature distribution
Summary
The polymerase chain reaction, PCR, was invented by K. Includes three basic reactions, denature, annealing, and extension (Adams et al, 2005), all of which have corresponding temperatures, range of temperatures, periods of reaction, and temperature uniformity. As these reactions absolutely influence the final products (Zhang and Xing, 2007), it is important to reduce the period of reaction and raise temperature uniformity. This study uses six heat sources to operate simulations at different heating speeds of 188, 300, 600, and 1200W, observes the period of reaction and speed of warming, and discusses the a multi-well vapor chamber heat spreader in the conclusion
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