Temperature distribution as function of time around a small spherical heat source of local magnetic hyperthermia

Abstract

A spherical region containing magnetic particles embedded in extended muscle tissue is taken as model of small breast carcinomas. Using analytically derived equations the spatial temperature distribution is calculated as function of the time for exposing to an alternating magnetic field. In vitro measurements with muscle tissue yielded such an agreement with the calculations that treatment of small tumors in slightly vascularized tissues on the base of mathematical predictions seems now to be more promising than in the past.