Temperature conversion factors, activation energy, relative substrate specificity and optimum pH of adenosine deaminase from human serum and tissues.

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Some properties of human serum and human tissue adenosine deaminase have been studied. Normal and pathological human serum adenosine deaminase and normal human tissue adenosine deaminase show the same activation energy values which are different from those found for the calf intestine enzyme. In the human species, but not in the bovine species, the serum enzyme differs from the tissue enzyme in pH optimum and relative substrate specificity for adenosine and 2’deoxyadenosine. Temperature conversion factors for human serum and calf intestine adenosine deaminase have also been calculated.