Abstract

Firms in high-technology industries face a complex set of challenges to innovate successfully and continuously to gain a sustainable competitive advantage. Innovative new R&D project sourcing choices top this list of difficult and nuanced choices that firms must make in pursuit of innovation. Our research makes a significant and novel contribution to this interesting discourse and critically examines the sourcing decision (i.e., open vs. closed innovation) in the context of new product development in the biopharmaceutical sector. Specifically, we apply a project-level typology along the dimensions of new R&D project source and project familiarity. Drawing from transaction cost economics (TCE) and the knowledge-based view (KBV) theories, we empirically test our theoretically developed hypotheses on a dataset of 2,971 biopharmaceutical R&D projects spanning from 1985 to 2016. Results from our robust analysis show that both new R&D project source and project familiarity have significant direct effects on focal project performance outcomes (defined in this paper as likelihood of termination). We also determine that focal project familiarity has a significant moderating effect on the relationship between project source and performance outcome.

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