Abstract

Background and aimsThe association between serum uric acid (SUA) and tea consumption has been studied in previous work, and there were arguments among various population group employed as well as different statistical approaches. The aim of this work is to investigate the tea effect on SUA levels among older adults by comparing three large-scale populations with both cross-sectional and longitudinal analyses.MethodWe examined the relationship between intake and SUA levels among older adults using linear regression. All the studies include the parameters SUA levels, tea intake, age, sex, education level, smoking status, alcohol drinking status, body mass index (BMI), and health history (diabetes, hypertension, and fasting plasma glucose). The cross-sectional analyses were conducted with 4579 older adults in the Weitang Geriatric Diseases Study (WGDS, ≥60 years), 2440 in the China Health and Nutrition Survey (CHNS, ≥60 years) and 1236 in the Chinese Longitudinal Healthy Longevity Survey (CLHLS, ≥62 years); and the longitudinal analyses were performed with 3870 (84.5%) in the WGDS and 420 (34.0%) in the CLHLS. Multivariable linear regression analyses were performed in both cross-sectional and longitudinal studies.ResultsCross-sectional studies showed that tea consumers tended to have higher SUA levels than non-tea consumers in all the three datasets (P < 0.05). However, longitudinal associations of SUA levels with tea consumption had no statistical significance (P>0.05). The results of sex-stratified analyses were consistent with those of the whole datasets.ConclusionsThis work implied that any possible association between tea consumption and SUA levels could be very weak.

Highlights

  • Background and aimsThe association between serum uric acid (SUA) and tea consumption has been studied in previous work, and there were arguments among various population group employed as well as different statistical approaches

  • Cross-sectional studies showed that tea consumers tended to have higher SUA levels than non-tea consumers in all the three datasets (P < 0.05)

  • This work implied that any possible association between tea consumption and SUA levels could be very weak

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Summary

Introduction

The association between serum uric acid (SUA) and tea consumption has been studied in previous work, and there were arguments among various population group employed as well as different statistical approaches. HUA is associated with increased hospitalization risks and healthcare expenditures [5]. The association between tea consumption and levels of serum uric acid (SUA) was inconsistent among different studies. Some studies supported that tea consumption could reduce SUA levels in both human beings [13] and animals [14, 15]. Other studies found that tea [16] or its extracts [17] were associated with a higher level of SUA. Non-significant association between tea consumption and SUA levels was reported in previous research [18]. The impact of tea consumption on levels of SUA is far from conclusive and needs further clarifications

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